Sunday

Manufacturing antibodies in an immune deficient world


















Our world seems to have changed in the past few decades.  Our medical-industrial complex has us convinced that our bodies cannot keep us healthy without vaccinations, drugs, or specially processed liquid foods (cradle to grave formulas).  We can live on top of a chemical dump called earth.  It's okay to breathe in the smog of chemicals from industries making more chemicals.  It's okay to swim in the oceans, lakes, and streams that are so polluted that its creatures wash ashore at regular intervals, dead from a sewer of chemical hells.  It's okay to eat and drink our fast convenient foods.  As long as we get our vaccinations, drugs, and special convenient foods with added vitamins, we will survive.  Like a pod of whales beaching themselves, we humans seem to have run aground in a desperate failing world.  Half breathing, half eating, half drinking ourselves to death:  as the corporate world bankrupts the world.

We believe that we can manufacture an immune system, after we have destroyed it. Men of science have the locks and keys to the molecular kingdom of antigens, antibodies.  Oh brave new world!  Oh hybridoma, mother of us all.  We can genetically engineer immunity.  Ya don't need to birth normally, breastfeed, eat real food, breath fresh air.  Lets fix the problem with molecular engineering and while we are at it we can make a little money.  Because the DNA of life on this planet is the almighty world of profit.

So what has this got to do with breastfeeding?  Not much.  It has alot to do with the understanding of the mammary gland and the value of human milk.  One thing that is well known is that human milk is very antigenic substance.  It was and is still used (in a more limited fashion since it requires injecting the antigenic substance into a mouse which creates ascites that are drained for use in manufacturing antibodies-painful to the mouse) to create polyclonal and monoclonal antibodies.  These antibodies are used to create various ELISA, Western blot,  assay kits to test our blood.  One rather famous monoclonal antibody is BrE3 which is used to diagnose breast cancer and also used in breast cancer therapies.  It was developed through the use of HMFG (human milk fat globule).  There are various patents regarding the use of HMFG in the creation of monoclonal antibodies.  We have patent #5075219 owned by John Muir Cancer & Aging Institute and filed in 1989 and invented by Roberto L. Ceriani and Jerry A. Peterson.

"The BrE3 monoclonal antibody was developed using normal delipidated human milk fat globules as the immunizing agent."

"The BrE3 monoclonal antibody is unique because of its exceptional specificity for a mucin-like glycoprotein complex of very high molecular weight present on the surface and in the cytoplasm of breast carcinoma cells and which expresses no specificity for normal tissue of the adrenal, brain, bladder, colon, esophagus, lymph node, myocardia, muscle , parathyroid, thyroid, mesothelia and liver.  Consequently the BrE3 monoclonal antibody can be useful in several ways."

I am fascinated by the use of HMFG.  How was it obtained?  Is it still needed to create these test kits?  It is also used in therapies.  How much is needed?  Women donate their milk and our science uses substances from that milk (HMFG) to create test kits and therapies for breast cancer (and other cancers, too).  My mother died of breast cancer at 48.  I was 14 when she died and the impact of her death on me and my family still haunts me.  Would I have been a different person, if she lived?  Did she really have breast cancer?  How come?  We lived near a nuclear reactor in Canada-Chalk River in the 50's, which had had a serious accident.  I feel childishly stuck on questions that cannot be answered now.  Yet as far as I know, our family history did not include breast cancer until she died from it.  Is a diagnosis kit for cancer a good thing?  I think most people think it is a good thing.  How accurate?  When you are not sick, but take a blood test that says cancer is there;  what does it mean?  I was told by a friend that her oncologist told her that cancer cells are always floating around in your blood stream.  If you have a healthy immune system, your body fights it off.  How does a blood test know that your body is fighting it or not fighting it?  And how does chemotherapy help an immune system fight off cancer.  All to often it seems that those who take chemotherapy for one cancer die a few years later from another cancer.  For me it is a rather curious world, where we don't try to change our polluted world, we just use man-made creations to try and save our health.  The world seems to actively sabotage normal birth and breastfeeding and the cost is sick people.  But sick people are good for the economy--at least in the USA, where healthcare is based on the profit system.  It seems like we are working this problem backwards.  We accept our polluted world, sabotage any semblance of healthy birth and breastfeeding, and wonder why the world is so sick. 
Copyright 2011 Valerie W. McClain

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